Folgende Songs werden standardmäßig auf dem Rock Band Datenträger vorhanden sein:
1960s
Rolling Stones "Gimme Shelter"
1970s
Aerosmith "Train Kept a Rollin\'"*
The Who "Won\'t Get Fooled Again"
Boston "Foreplay/Long Time"
Mountain "Mississippi Queen" (cover)
The Police "Next to You"
David Bowie "Suffragette City"
Black Sabbath "Paranoid" (cover)
Blue Oyster Cult "Don\'t Fear the Reaper"
The Ramones "Blitzkrieg Bop"
Deep Purple "Highway Star"
KISS "Detroit Rock City"
Molly Hatchet "Flirtin\' With Disaster"
The Outlaws "Green Grass & High Tides" (cover)
Sweet "Ballroom Blitz" (cover)
1980s
Rush "Tom Sawyer"*
Bon Jovi "Wanted Dead or Alive"
The Clash "Should I Stay or Should I Go"
Faith No More "Epic"
R.E.M. "Orange Crush"
Pixies "Wave of Mutilation"
Iron Maiden "Run to the Hills" (cover)
1990s
Foo Fighters "Learn to Fly"
Metallica "Enter Sandman"
Nirvana "In Bloom"
Stone Temple Pilots "Vasoline"
Weezer "Say It Ain\'t So"
Smashing Pumpkins "Cherub Rock"
Radiohead "Creep"
Beastie Boys "Sabotage"
Hole "Celebrity Skin"
Garbage "I Think I\'m Paranoid"
Soundgarden "Black Hole Sun"
2000s
The Hives "Main Offender"
Queens of the Stone Age "Go With the Flow"
The Strokes "Reptilia"
Jet "Are You Gonna Be My Girl"
OK Go "Here It Goes Again"
Nine Inch Nails "The Hand That Feeds"
Yeah Yeah Yeahs "Maps"
Red Hot Chili Peppers "Dani California"
Coheed & Cambria "Welcome Home"
Fallout Boy "Dead on Arrival"
The Killers "When You Were Young"
New Pornographers "Electric Version"
Freischaltbare Songs
Bang Camaro "Pleasure (Pleasure)"
+ 12 weitere, die noch bekannt gegeben werden
Darüber hinaus wird das Spiel noch jede Menge herunterladbare Songs anbieten. Zu schade nur, dass das Spiel erst nächstes Jahr in Europa erscheinen wird.